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Description:
This test is designed to measure sufficient intake of antioxidant nutrients through the detection of oxidative damage to DNA.


The biomarker, 8-hydroxy-2'-deoxyguanosine (8OHdG) has been used to estimate DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons. In recent years, 8-OHdG has been used widely in many studies not only as a biomarker for the measurement of endogenous oxidative DNA damage but also as a risk factor for many diseases including cancer.


This mechanism occurs through the interaction of reactive oxygen species with DNA and RNA. This interaction produces oxidation products of these base rings. DNA repair enzymes must remove the damaged bases in order to maintain the viability of DNA and RNA. Oxidation of the nucleoside guanosine produces 8OHdG. The concentration of 8OHdG in urine has thus been studied as an accurate measure of the rate of polynucleotide oxidative damage. Elevated 8OHdG indicates that antioxidant nutrient intake may be insufficient. Additionally, toxicants and lifestyle stress factors may contribute to increased oxidative challenge.
Tests type:
Oxidative stress: cancer markers, antioxidant marker
 
Symptoms and conditions:
  • Atherosclerosis
  • Body mass index
  • Cancer
  • Diabetes
  • Environmental exposure
  • Gender
  • Hematological diseases
  • Hyperglycemia
  • High blood pressure
  • Liver disease
  • Lung cancer
  • Parkinson’s disease
  • Poor lifestyle habits
  • Sleep apnea
  • Smoking
  • Toxic exposure
 
Analytes measured:
  • 8-hydroxy-2'-deoxyguanosine (8OHdG)
  • Creatinine
 
Method:
Liquid chormatography / tandem mass-spectrometry

​
EUR 140,00
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  • Hem
  • LEX NATURA
  • Företagshälsa
  • Nature Clinic
    • Ortomolekylär Medicin
    • Behandlingsförlopp
    • Hälsoproblem >
      • Irritabel Tarm
      • Hormonrubbningar
      • Uppblåsthet
      • ​Förstoppning
      • Morbus Crohn
      • Ulcerös Kolit
      • Glutenintolerans
      • Celiaki
      • Mat Intolerans
      • Pollenallergi
      • Födoämnesallergier
      • Borreliose
      • Adrenal Trötthet
      • Kroniskt Trötthetssyndrom
      • Stress
      • Autisme (ASF)
      • Artrit
    • Health Mentor: Amadeus
    • Dr. Allan Fjelstrup
  • Laboratories
    • Category >
      • Toxicity >
        • Urine Toxic and Essential Elements (timed or 24 hour) Post
        • Urine Toxic Metals (timed or 24 hour) Pre
      • Hormonal >
        • Adrenal Stress
        • Comprehensive Female I (Saliva: E2, Pg, T, DS, Cx4) (Blood Spot: TSH, fT3, fT4, TPO)
        • Complete Thyroid Profile (TSH, fT3, fT4, & TPO)
        • Complete Iodine Thyroid w/ elements & Adrenal stress
      • Hair Analysis
      • Borrelia and Co-Infections >
        • Babesia DNA PCR
        • Babesia IgG antibodies
        • Bartonella DNA-PCR
        • The Bartonella IgG antibodies
        • Lyme Elispot LTT
        • Epstein-Barr Virus Antibodies
        • Ehrlichia DNA-PCR
        • kolesterolsänkande statiner
      • Oxidative Stress
      • Genetic >
        • DNA Diet
        • DNA Health
        • DNA Oestrogen
        • DNA Sport
        • mycardioRx
        • mygeneRx Comprehensive PGX Panel
        • mypainRx
        • mypsychRx
      • Gastrointestinal >
        • Comprehensive Stool Analysis & Parasitology x2 (CSAPx2)
        • Comprehensive Parasitology x2 (CPx2)
      • Cardiovascular
      • Condition >
        • Coeliac disease >
          • Biocard™_Home Celiac Test
          • Immuno 1 IgG + Candida
          • Immuno 1 IgG + Candida + Gliadin
          • Immuno 1 IgG + Gliadin
          • Immuno Candida (Immunodiffusion & IgG)
          • Immuno Gliadin (IgA & IgG)
          • Immuno IgG 115 (DK result)
        • Diabetes >
          • ADMA Assay
          • Bisphenol A (BPA) Profile + Phthalates + Parabens
          • Bisphenol A (BPA) Profile - Urine
          • Cardio ION
          • CardioMetabolic Profile I (Insulin, hsCRP, HbA1c, TG, CH, LDL, HDL, VLDL)
          • Fasting Insulin - DBS
          • Fertility Profile (Saliva: Cx4) (Blood Spot: E2, Pg, T, DS, SHBG, TSH, fT3, fT4, TPO, FSH, LH)
          • HbA1c - DBS
          • PCBs Profile - Serum
          • Volatile Solvents Profile
        • Depression >
          • Adrenal Stress
          • Complete Iodine Thyroid w/ elements & Adrenal stress
          • Complete Iodine Thyroid w/elements
          • Complete Thyroid Profile (TSH, fT3, fT4, & TPO) - BLOODSPOT
          • Comprehensive Female I (Saliva: E2, Pg, T, DS, Cx4) (Blood Spot: TSH, fT3, fT4, TPO)
          • Comprehensive Female II (Saliva: Cx4) (Blood Spot: E2, Pg, T, SHBG, DS, TSH, fT3, fT4, TPO)
          • Comprehensive Male I (Saliva: E2, T, DS, Cx4) (Blood Spot: PSA, TSH, fT3, fT4, TPO)
          • Comprehensive Male II (Saliva: Cx4) (Blood Spot: E2, T, DS, SHBG, PSA, TSH, fT3, fT4, TPO)
          • Bloodspot IgG4 (30 foods)
          • Bloodspot Amino Acids 20
          • Female Blood Profile II (E2, Pg, T, DS, C, SHBG, TSH, fT3, fT4, & TPO)
          • Organix Comprehensive
          • Bloodspot Amino Acids 11
        • Anxiety >
          • Comprehensive Stool Analysis & Parasitology x2 (CSAPx2)
          • Adrenal Stress
          • Organix Comprehensive
          • Comprehensive Parasitology x2 (CPx2)
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